Tolerability of diclofenac sodium 1% gel with concomitant medications known to interact with diclofenac
نویسندگان
چکیده
منابع مشابه
Tolerability of diclofenac sodium 1% gel with concomitant medications known to interact with diclofenac
BACKGROUND Topical diclofenac sodium 1% gel (DSG) has demonstrated efficacy and tolerability in patients with osteoarthritis (OA) of the knees or hands, including elderly patients and those with an increased risk of gastrointestinal, cardiovascular, and renal adverse events (AEs). Medications known to interact with diclofenac were disallowed in a clinical trial of DSG for knee OA; however, pati...
متن کاملLong-term tolerability of topical diclofenac sodium 1% gel for osteoarthritis in seniors and patients with comorbidities
BACKGROUND Adverse events associated with nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat knee and hand osteoarthritis may be more frequent in certain patient populations. Topical NSAIDs, such as diclofenac sodium 1% gel (DSG), have equivalent efficacy and fewer adverse events compared with oral NSAIDs. This post hoc analysis assessed the long-term tolerability of DSG in elderly pat...
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Background Newer drug delivery systems such as transdermal patches using pain relieving or modifying agents emerged as a mainstream treatment protocol for management of pain on the outpatient basis. The administration of diclofenac 100 mg in the transdermal patch in the patients having dental pain due to periapical/periodontal infections was evaluated. Materials and Methods Ninety patients of...
متن کامل[Diclofenac of rapid effect (Diclorapid) with better gastric tolerability].
The diclofenac of rapid effect (Diclorapid) that has better gastric tolerability is presented.
متن کاملA pharmacoeconomic comparison of misoprostol/diclofenac with diclofenac.
OBJECTIVES To estimate the economic impact of misoprostol/diclofenac in a fixed combination tablet compared with diclofenac. DESIGN Cohort study with a prospectively constructed, population-based, record-linkage database containing details of exposure to all community dispensed NSAIDs and all admissions to hospital for upper gastrointestinal (GI) diagnoses. Costs associated with each study dr...
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ژورنال
عنوان ژورنال: The Journal of Pain
سال: 2012
ISSN: 1526-5900
DOI: 10.1016/j.jpain.2012.01.358